5-Amino-1MQ: NNMT Inhibitor
It is not a peptide, but a small molecule that inhibits the NNMT enzyme. In doing so it raises cellular NAD+ and, in preclinical models, reduces fat storage in the adipocyte.
What 5-Amino-1MQ is
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule — not a peptide — designed as an inhibitor of the NNMT enzyme (nicotinamide N-methyltransferase). It is included here for its metabolic relevance and its place in fat-loss research stacks.
NNMT inhibition
NNMT methylates nicotinamide, consuming NAD+ and SAM. In adipose tissue, elevated NNMT is associated with greater fat storage. Inhibiting it, according to the hypothesis, preserves NAD+, increases adipocyte energy expenditure and reduces lipogenesis.
Published studies
In animal models, NNMT inhibition or silencing protected against diet-induced obesity and improved metabolic parameters. The evidence is preclinical; there are no large published clinical trials.
Dosing context
Being a small molecule, in research it is handled orally in daily milligram doses. Descriptive context from the literature, not a clinical recommendation.
Related products
⚠ For research use only. Not medical advice.