Renova Guides
Knowledge base for peptide research. Mechanisms, published studies, reconstitution, stacks โ curated by our team.
MOTS-c: The Mitochondrial Peptide Explained
Encoded in mitochondrial DNA, MOTS-c regulates metabolism, insulin sensitivity, and exercise response. Why it's become one of the most studied compounds in metabolic longevity research.
Read guide โLongevity ยท Anti-agingNAD+: The Coenzyme of Cellular Energy and Longevity
The redox coenzyme that drops ~50% by midlife. Mitochondrial energy, DNA repair, sirtuins, and why it's central to longevity research.
Read guide โAntioxidant ยท LongevityGlutathione: The Body's Master Antioxidant
The most abundant intracellular antioxidant tripeptide. GSH/GSSG redox cycle, hepatic detoxification, and why the injectable route is studied.
Read guide โMitochondrial ยท LongevitySS-31 (Elamipretide): The Mitochondria-Targeting Peptide
A tetrapeptide that concentrates in the inner mitochondrial membrane and binds cardiolipin: stabilizes cristae, improves the electron transport chain, and lowers ROS.
Read guide โLongevity ยท Anti-agingEpithalon: Telomeres, the Pineal Gland and Longevity
A pineal-derived bioregulator tetrapeptide (AEDG). Telomerase, melatonin rhythm, and longevity models โ what the evidence shows and where it's preliminary.
Read guide โAnti-inflammatoryKPV: Anti-inflammatory Tripeptide for Skin & Mucosa
The ฮฑ-MSH C-terminal fragment with potent anti-inflammatory activity in psoriasis, eczema, colitis, and wound healing models. Why it's in GLOW and KLOW.
Read guide โImmune ยท ImmunomodulatorThymosin Alpha-1: The Thymic Immunomodulating Peptide
A 28-amino-acid thymic peptide (thymalfasin / Zadaxin). Modulates T cells, NK cells and dendritic cells via TLRs. Evidence in chronic hepatitis, sepsis and oncology โ one of the most studied immunomodulatory peptides.
Read guide โRegeneration ยท Anti-agingGHK-Cu: Copper-Tripeptide, Dermal Regenerator & Senescence
Pickart isolated it from human plasma in 1973. Regulates collagen, reverses senescence markers in fibroblasts, and is the regenerative anchor in GLOW and KLOW.
Read guide โRepair ยท BlendGLOW vs KLOW: Which Repair Blend to Choose
BPC-157 + GHK-Cu + TB-500 (GLOW) vs the same + KPV (KLOW). What each component adds and when to choose each blend.
Read guide โGrowth HormoneCJC-1295 + Ipamorelin: The Most-Studied GH Stack
GHRH + ghrelin secretagogue. Why this combination produces an endogenous GH pulse superior to either alone โ and how to dose the pre-mixed blend.
Read guide โGrowth HormoneTesamorelin: GHRH Analog and Visceral Fat
A stabilized GHRH analog that stimulates pulsatile endogenous GH. Most studied for visceral and liver fat reduction. How it differs from exogenous GH and secretagogues.
Read guide โMaster Guide ยท Fat LossFat Loss: Complete Peptide Guide (2026)
From GLP-1 agonists (Tirzepatide, Retatrutide) to adjuvants (5-Amino-1MQ, SLU-PP-332, AOD-9604, MOTS-c). The complete map of what each compound does and how they stack in research.
Read guide โComparisonTirzepatide vs Retatrutide: Mechanism, Studies and Dose Differences
Technical comparison: FDA-approved GLP-1/GIP dual agonist vs Phase III triple agonist.
Read guide โGLP-1 ยท MetabolicRetatrutide: Triple GLP-1 / GIP / Glucagon Agonist
The first triple agonist in clinical research. Mechanism of all three receptors, Phase 2 results (NEJM 2023), the Phase 3 TRIUMPH program, and how it differs from tirzepatide and semaglutide.
Read guide โPeptideBPC-157: Mechanism, Published Studies and Recovery Applications
The most-studied gastric body peptide in animal models of tissue repair.
Read guide โRecovery ยท BlendWolverine Stack: BPC-157 + TB-500 Recovery Synergy
Why BPC-157 + TB-500 is the most-studied combination in injury recovery research programs โ and how to dose the pre-mixed 10 mg + 10 mg blend.
Read guide โPracticalPeptide Reconstitution: Complete Guide with Examples
How to reconstitute a lyophilized vial step-by-step, formulas, U100 units.
Read guide โMechanismsGLP-1 Agonists: How Incretin Analogs Work
GLP-1, GIP, glucagon โ biology behind Tirzepatide, Retatrutide, Semaglutide.
Read guide โSleep ยท CognitiveDSIP: Delta Sleep-Inducing Peptide
A nonapeptide isolated in 1977 during delta-wave sleep. A neuromodulator of sleep and the stress axis โ not a classic sedative. What the evidence says.
Read guide โCognitive ยท NootropicsSemax and Selank: The Russian Peptide Nootropics
Semax (BDNF/NGF, focus and neuroprotection) and Selank (anxiolytic without sedation, GABA/serotonin). What each does and when to research each peptide.
Read guide โCognitive ยท NeuroPinealon: A Peptide Bioregulator for Neuroprotection
A short tripeptide (EDR) from the Khavinson family. Neuroprotection, oxidative stress, and cognition in preclinical models. Its relationship to Epithalon.
Read guide โMelanocortin ยท NeuroPT-141 (Bremelanotide): A Melanocortin Receptor Agonist
An ฮฑ-MSH analog acting centrally at the MC4R receptor โ a different mechanism from vascular agents. The melanocortin system and clinical context.
Read guide โ